Today's Updates

Indian states ban cough syrup linked to child deaths
Published Date: 06 Oct 2025

At least three Indian states have banned a cough syrup after several children died allegedly after consuming the product, said local authorities and reports.

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Scientists identify a new dendritic nanotubular network in the brain that may contribute to Alzheimer's disease
Published Date: 06 Oct 2025

Neurons in the brain communicate with each other through synapses—connection points that allow the passage of electrical and chemical signals. In non-neuronal cells, direct cell-to-cell connections have been found to occur ...

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September's FDA Focus: Approvals and pipeline updates in pediatrics
Published Date: 06 Oct 2025

September's FDA Focus: Approvals and pipeline updates in pediatrics

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Latest News

Stabilization of neuropathy scores seen after gene editing therapy for rare nerve disease

University College London's National Amyloidosis Center leads a multinational team reporting that a single infusion of an in vivo gene-editing therapy (nexiguran ziclumeran) produced rapid, deep, and durable reductions in ...

Cracking the code: Shared genes connect osteoporosis and rotator cuff tears

Scientists have found a direct link between osteoporosis and rotator cuff tears, two conditions that often develop with age. Using health and genetic data from hundreds of thousands of people, researchers showed that fragile ...

Genetic and behavioral links found between musical rhythm perception and developmental language disorders

In a paper published in Nature Communications, researchers at Vanderbilt University Medical Center's Department of Otolaryngology–Head and Neck Surgery leveraged two main studies—one focused on behavior and one focused ...

Introducing the 'human repairome,' a catalog of DNA 'scars' that may help define personalized cancer treatments

You can always be judged by your scars. This is the idea that sums up one of the new advances in basic and biomedical research published in the journal Science by the Spanish National Cancer Research Center (CNIO). It is ...

Health insurers are offering DNA testing to see how some medicines might work. What to know before you opt in

Two major Australian health insurers, Bupa and Medibank, have started offering genetic testing meant to tell you your likely reaction to certain medications.

A polygenic risk score may predict future breast cancer in patients with early-stage diagnoses

A retrospective study found that the 313-SNP breast cancer polygenic risk score (PRS313) blood test could predict future incidents of breast cancer in women diagnosed with ductal carcinoma in situ (DCIS) or lobular carcinoma ...

Discovery of treatable mesothelioma variant highlights importance of genetic screening and early detection

University of Hawaiʻi Cancer Center researchers have identified a new, less aggressive form of mesothelioma that offers patients greater hope for survival and treatment success. Led by Michele Carbone and Haining Yang, the ...

Dads influence embryo growth via molecular signatures, research reveals

Over the past few decades, growing evidence has challenged the belief that inheritance is governed solely by DNA sequences. Scientists now recognize the crucial role of epigenetic inheritance—the transmission of biological ...

Enlarged cancer cell nuclei may limit spread rather than signal severity

In tissue biopsies, cancer cells are frequently observed to have nuclei (the cell's genetic information storage) that are larger than normal. Until now, this was considered a sign that the cancer was worsening, but the exact ...

How gene mutations drive dementia in Parkinson's disease

Parkinson's disease causes both movement and cognitive deficits, and for a long time both were thought to be caused by the accumulation of a protein called alpha-synuclein in the brain. But a new Nature Communications study ...

How a 'speech gene' could help treat Huntington's

In fatal genetic diseases like Huntington's and spinocerebellar ataxia, proteins develop long stretches of repeating letters that are prone to sticking together like Velcro.

A more precise CRISPR platform enables large-scale gene screening in live mouse brains

Over the past few decades, biomedical researchers and neuroscientists have devised increasingly advanced techniques to study and alter neurophysiological processes. These include CRISPR (Clustered Regularly Interspaced Short ...

Genetic screening technique could enhance CAR-T therapies for multiple myeloma and other cancers

Researchers from Mass General Brigham and the Broad Institute of MIT and Harvard have identified genetic modifications that can improve the efficacy of chimeric antigen receptor (CAR)-T cell treatment—an immunotherapy that ...

Supercentenarian's biology shows the delicate balance of longevity

Recent studies suggest that the steady rise in life expectancy observed over the past 200 years has now stagnated. Data indicate that a limit has been reached, and that medical and health care advances no longer affect longevity ...

Early changes during brain development may hold the key to autism and schizophrenia

Researchers at the University of Exeter have created a detailed temporal map of chemical changes to DNA through development and aging of the human brain, offering new insights into how conditions such as autism and schizophrenia ...

Enhanced CAR T cells emerge from genetic screening

CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in modern medicine. Equipping T cells, a key cell type of the immune system, with a "chimeric antigen ...

Latest News

Stabilization of neuropathy scores seen after gene editing therapy for rare nerve disease

University College London's National Amyloidosis Center leads a multinational team reporting that a single infusion of an in vivo gene-editing therapy (nexiguran ziclumeran) produced rapid, deep, and durable reductions in ...

Cracking the code: Shared genes connect osteoporosis and rotator cuff tears

Scientists have found a direct link between osteoporosis and rotator cuff tears, two conditions that often develop with age. Using health and genetic data from hundreds of thousands of people, researchers showed that fragile ...

Genetic and behavioral links found between musical rhythm perception and developmental language disorders

In a paper published in Nature Communications, researchers at Vanderbilt University Medical Center's Department of Otolaryngology–Head and Neck Surgery leveraged two main studies—one focused on behavior and one focused ...

Introducing the 'human repairome,' a catalog of DNA 'scars' that may help define personalized cancer treatments

You can always be judged by your scars. This is the idea that sums up one of the new advances in basic and biomedical research published in the journal Science by the Spanish National Cancer Research Center (CNIO). It is ...

Health insurers are offering DNA testing to see how some medicines might work. What to know before you opt in

Two major Australian health insurers, Bupa and Medibank, have started offering genetic testing meant to tell you your likely reaction to certain medications.

A polygenic risk score may predict future breast cancer in patients with early-stage diagnoses

A retrospective study found that the 313-SNP breast cancer polygenic risk score (PRS313) blood test could predict future incidents of breast cancer in women diagnosed with ductal carcinoma in situ (DCIS) or lobular carcinoma ...

Discovery of treatable mesothelioma variant highlights importance of genetic screening and early detection

University of Hawaiʻi Cancer Center researchers have identified a new, less aggressive form of mesothelioma that offers patients greater hope for survival and treatment success. Led by Michele Carbone and Haining Yang, the ...

Dads influence embryo growth via molecular signatures, research reveals

Over the past few decades, growing evidence has challenged the belief that inheritance is governed solely by DNA sequences. Scientists now recognize the crucial role of epigenetic inheritance—the transmission of biological ...

Enlarged cancer cell nuclei may limit spread rather than signal severity

In tissue biopsies, cancer cells are frequently observed to have nuclei (the cell's genetic information storage) that are larger than normal. Until now, this was considered a sign that the cancer was worsening, but the exact ...

How gene mutations drive dementia in Parkinson's disease

Parkinson's disease causes both movement and cognitive deficits, and for a long time both were thought to be caused by the accumulation of a protein called alpha-synuclein in the brain. But a new Nature Communications study ...

How a 'speech gene' could help treat Huntington's

In fatal genetic diseases like Huntington's and spinocerebellar ataxia, proteins develop long stretches of repeating letters that are prone to sticking together like Velcro.

A more precise CRISPR platform enables large-scale gene screening in live mouse brains

Over the past few decades, biomedical researchers and neuroscientists have devised increasingly advanced techniques to study and alter neurophysiological processes. These include CRISPR (Clustered Regularly Interspaced Short ...

Genetic screening technique could enhance CAR-T therapies for multiple myeloma and other cancers

Researchers from Mass General Brigham and the Broad Institute of MIT and Harvard have identified genetic modifications that can improve the efficacy of chimeric antigen receptor (CAR)-T cell treatment—an immunotherapy that ...

Supercentenarian's biology shows the delicate balance of longevity

Recent studies suggest that the steady rise in life expectancy observed over the past 200 years has now stagnated. Data indicate that a limit has been reached, and that medical and health care advances no longer affect longevity ...

Early changes during brain development may hold the key to autism and schizophrenia

Researchers at the University of Exeter have created a detailed temporal map of chemical changes to DNA through development and aging of the human brain, offering new insights into how conditions such as autism and schizophrenia ...

Enhanced CAR T cells emerge from genetic screening

CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in modern medicine. Equipping T cells, a key cell type of the immune system, with a "chimeric antigen ...

News All Time

A more precise CRISPR platform enables large-scale gene screening in live mouse brains

Over the past few decades, biomedical researchers and neuroscientists have devised increasingly advanced techniques to study and alter neurophysiological processes. These include CRISPR (Clustered Regularly Interspaced Short ...

Not all ALK fusions act the same: Variants influence treatment success in lung cancer

About 5% of lung adenocarcinomas, one of the most common forms of lung cancer, are driven by a faulty fusion of two genes, EML4 and ALK. This fusion results in different variants, and until now, clinicians have treated all ...

Novel gene editing technology enables selective destruction of cancer cell DNA using fewer targets

Researchers from the Department of Biomedical Engineering at UNIST and the Center for Genomic Integrity at the Institute for Basic Science (IBS) have announced an advance in cancer gene therapy. Their innovative method enables ...

Diagnostic tool enables rapid leukemia subtype classification

Researchers at Dana-Farber Cancer Institute have developed a diagnostic tool that could transform the way acute leukemia is identified and treated. The tool, called MARLIN (Methylation- and AI-guided Rapid Leukemia Subtype ...

Metabolic markers may predict breast cancer in high-risk women

Breast cancer remains the most common cancer and the leading cause of cancer-related death among women worldwide, with incidence rates continuing to rise. However, known risk factors, including genetics and lifestyle, do ...

Single drug provides first evidence of 'nearly universal' pharmacological chaperone for rare disease

A study published in Nature Structural & Molecular Biology is the first time researchers have shown evidence that a single drug, already licensed for medical use, can stabilize nearly all mutated versions of a human protein, ...

Largest genetic study to date identifies 13 new DNA regions linked to dyslexia

Dyslexia is a neurodevelopmental condition estimated to affect between 5–10% of people living in most countries, irrespective of their educational and cultural background. Dyslexic individuals experience persistent difficulties ...

Telomere protection failure: How genetic mutations cause pulmonary fibrosis

A research group from the National Cancer Research Center (CNIO) has found that an alteration in the POT1 gene prevents lung tissue from regenerating, which over time makes breathing difficult. The mutation prevents telomeres, ...

Genetic test predicts response to weight-loss drugs

Mayo Clinic researchers have developed a genetic test that can help predict how people will respond to weight loss medications such as GLP-1s.

CRISPR approach offers hope for severe childhood brain disorder

When brain development gets off to a bad start, the consequences are lifelong. One example is a condition called SCN2A haploinsufficiency, in which children are born with just one functioning copy of the SCN2A gene—instead ...

Study identifies genetic loci that link brain structure and various psychiatric disorders

The development of many psychiatric disorders, including depression, schizophrenia and bipolar disorder, is known to be in great part influenced by genetics. Past research has identified various genes that appear to be associated ...

Late-life virginity: Mapping genetic, psychological and social factors in adults who have never had sex

Researchers from Karolinska Institutet, the Max Planck Institute for Empirical Aesthetics (Germany), Amsterdam UMC (Netherlands), in collaboration with other international partners, have conducted the most extensive study ...

Reprogramming the epigenetic code affects growth and survival of tumor cells in multiple myeloma

In the cancer type multiple myeloma, the malignant cells differ significantly from normal cells regarding the layer of chemical "tags" on DNA and proteins that control whether genes are turned on or off. These "tags" affect ...

AI-powered CRISPR could lead to faster gene therapies

Stanford Medicine researchers have developed an artificial intelligence tool to help scientists better plan gene-editing experiments. The technology, CRISPR-GPT, acts as a gene-editing "copilot" supported by AI to help researchers—even ...

Finding patterns in genetic uncertainty: Clues for inborn errors of immunity

Behind every unexplained medical condition is a patient hoping for clarity and understanding. For people with suspected inborn errors of immunity (IEIs), genetic testing can facilitate individually tailored and effective ...

Genetic variants may explain why obesity affects people differently

An international team of researchers led by Icahn School of Medicine at Mount Sinai and the University of Copenhagen in Denmark has pinpointed some of the reasons why obesity does not affect everyone in the same way. Their ...

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