Understanding Axitinib: What You Need To Know For Your Treatment Plan

Author Name : Dr. Shilpa Choudhary Ambekar

Oncology

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Axitinib is a targeted therapy drug used in the treatment of metastatic renal cell carcinoma (RCC). It works to block certain proteins, known as vascular endothelial growth factor receptors (VEGFRs), from growing and spreading. This allows for improved outcomes in patients with this form of cancer. However, like other treatments, there are risks and side effects associated with its use. In this article, we will discuss what you need to know about axitinib in order to make informed decisions about your treatment plan. We will explore how it works, the different types available, common side effects associated with use, and other important information that can help you feel confident in your choice of treatment.

What is Axitinib?

Axitinib is a targeted cancer therapy that works by inhibiting the activity of tyrosine kinase enzymes. These enzymes are involved in the growth and spread of cancer cells. Axitinib is used to treat renal cell carcinoma (RCC), a type of kidney cancer. It is typically used after other treatments, such as surgery, have failed. Axitinib may also be used to treat other types of cancers, such as thyroid cancer or non-small cell lung cancer (NSCLC).

Axitinib belongs to a class of drugs known as kinase inhibitors. Kinase inhibitors work by blocking the activity of certain enzymes, which can help stop the growth and spread of cancer cells. Axitinib is a targeted therapy, which means it targets specific molecules that are involved in the growth and spread of cancer cells. Axitinib inhibits the activity of tyrosine kinase enzymes. These enzymes are found in healthy cells, but they are overactive in cancer cells. By inhibiting these enzymes, axitinib can help stop the growth and spread of cancer cells.

How does Axitinib work?

Axitinib works by inhibiting the vascular endothelial growth factor (VEGF) receptor. This protein is responsible for the growth and development of new blood vessels. When the VEGF receptor is inhibited, blood vessel growth is prevented, which in turn slows down the growth of cancerous tumors. Axitinib has been shown to be effective in treating several types of cancer, including renal cell carcinoma, gastrointestinal stromal tumor, and thyroid cancer.

Who should take Axitinib?

  • Axitinib is a prescription medication used to treat certain types of kidney cancer. It is also used to treat a type of thyroid cancer that cannot be treated with surgery. Axitinib is a type of targeted therapy, which means it targets specific molecules involved in the growth and spread of cancer cells.

  • Axitinib may be used alone or in combination with other cancer treatments

  • Axitinib is generally well-tolerated, but like all medications, it comes with the potential for side effects. Some common side effects include fatigue, diarrhea, nausea, and decreased appetite. Most side effects are mild and can be managed with medication or other interventions.

What are the side effects of Axitinib?

The most common side effects of Axitinib are diarrhea, fatigue, high blood pressure, loss of appetite, and nausea. Less common side effects include bleeding, brain hemorrhage, heart attack, kidney failure, and liver damage. Some of the more rare side effects include hair loss, skin rash, and vision changes.

How is Axitinib taken?

Axitinib is a pill that is taken by mouth. It is usually taken once a day with or without food. If you take it with food, you may take it with or without a meal. Try to take it at the same time each day.

If you miss a dose of axitinib, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Conclusion

Axitinib is a powerful cancer-fighting drug that can be used to treat certain types of tumors. While the side effects and risks associated with its use must always be taken into account, it has been proven effective in many cases. With careful monitoring and guidance from your oncologist or hematologist, axitinib can be incorporated into an individualized treatment plan that helps you manage your disease while minimizing any potential adverse reactions.


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